Axon degeneration is a tightly regulated, self-destructive program that is a critical feature of many neurodegenerative diseases, but the molecular mechanisms regulating this program remain poorly understood.Here, we identify S-phase kinase-associated protein 1A (Skp1a), a core component of a Skp/Cullin/F-box (SCF)-type neutral checkered phone case
Despite recent progress, the causes and pathophysiology of post-traumatic stress disorder (PTSD) remain poorly understood, partly because of ethical limitations inherent to human studies.One approach to circumvent this obstacle is to study PTSD in a valid animal model of the human syndrome.In one such model, extreme and long-lasting behavioral ill
Multi-speed transmission can greatly improve the power and economic performance of electric vehicles (EVs) compared with single-speed transmission.Gear ratio is the key design parameter of multi-speed transmission.Optimizing gear ratios can further improve vehicle performance.Most of the existing optimization methods of gear ratios take the power a
The development and optimization of renewable energy systems are some of the most necessary topics to advance towards secure and sustainable energy models.Photovoltaic energy is one of those sustainable options that could contribute to the reduction of greenhouse gas emissions.The optimal angle of solar incidence producing the highest absorption in
Abstract Impairment of neuromuscular function in neurological disorders leads to reductions in epiphone slash anaconda muscle force, which may lower quality of life.Rehabilitation robots that are equipped with sensors are able to quantify the extent of muscle force impairment and to monitor a patient during the process of neurorehabilitation with s